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As of 2011, ARC was no longer in the Plasma Services industry. blood bank to implement a Nucleic acid testing (NAT) study.

The Red Cross supplies Baxter Bio Sciences with items for the manufacturing of plasma products. This process is different from traditional testing because it looks for the genetic material of HIV and hepatitis C (HCV), rather than the body's response to the disease. These tests detect the genetic material of a transfusion-transmitted virus like HIV without waiting for the body to form antibodies, potentially offering an important time advantage over current techniques.

Leukocytes in stored blood products can have a variety of biological effects, including depression of immune function, which can result in organ failure and death.

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Barton was unable to build up a staff she trusted and her fundraising was lackluster. Professional social work experts took control and made the group a model of Progressive Era scientific reform.Community-based blood centers supply 50% and 6% is collected directly by hospitals.In December 2004, ARC completed its largest blood processing facility in the United States in Pomona, California, on the campus grounds of the California State Polytechnic University, Pomona.The first chapters opened in upstate New York, where she had connections.Barton led one of the group's first major relief efforts, a response to the September 4–6, 1881 Great Fire of 1881 (Thumb Fire) in the Thumb region of Michigan. The next major disaster was the Johnstown Flood, which occurred on May 31, 1889.Approximately 500,000 Red Cross volunteers, including Fema Corps and Ameri Corps members, and 30,000 employees annually mobilize relief to people affected by more than 67,000 disasters, train almost 12 million people in necessary medical skills and exchange more than a million emergency messages for U. military service personnel and their family members.

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